![]() Depending on students’ backgrounds, it may be helpful to pause the animation at various points to identify the molecules and describe their interactions. Our comprehensive genetics unit takes learners from the earliest experiments that revealed the basis of genetics through the intricacies of DNA to current applications in the emerging studies of biotechnology and genomics. This animation brings the DNA replication process to life, showing three-dimensional representations of the molecules involved. ![]() These two different mechanisms of copying DNA occur because DNA polymerase can only synthesize DNA in the 5' to 3' direction. The proteins required to initiate, coordinate, and complete the replication process are best characterized in model organisms such as Escherichia coli. DNA polymerase copies the lagging strand in sections. The 5' strand is also known as the lagging strand. DNA replication stress is characterized by impaired replication fork progression, causing some of the replication forks to collapse and form DNA breaks. The 3' DNA strand is also known as the leading strand DNA polymerase copies the leading strand to produce a complementary strand. Genes through DNA Methylation National Cancer Institute DNA Replication Wiley. ![]() The two strands are referred to as the 3' and 5' strands based on the direction by which the component nucleotides are joined. Prefixes Roots & Suffixes Biology Animations BBC Howard Hughes Medical. This animation shows the process of DNA replication, including details about how the mechanism differs between the leading and lagging strand.ĭNA replication starts with the separation of the two DNA strands by the enzyme helicase. ![]()
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